Cyclomix – CGMP Model Cyclo Mixture

Design: High-speed paddle mixer with high shear & impact forces for cohesive powders, slurries, and liquids.

Key Applications:

• Intensive mixing of cohesive powders, slurries, and liquids

• Coating (powder/liquid on powder)

• Agglomeration (via temperature/moisture)

• Pigment dispersion

• Vacuum drying (low temp, liquid recovery)

• Spheronization of particles

• Grinding/de-agglomeration

• Heating/cooling

Working Principle:

• Conical vessel with a high-speed rotor (tip speed: 3–30 m/s).

• Centrifugal force pushes material to the wall → upward movement.

• Domed cover redirects material to the center.

• Impact blade breaks agglomerates for uniform mixing.

• Ultra-fast batch processing with homogeneous output.

Key Features:

1. High Shear + Impact Mixing – Ideal for sticky/cohesive products.

2. Precise Temperature Control – Jacketed wall for heating/cooling.

3. Seals Above Product Zone – No contact between bearings/seals and product (top-driven rotor).

4. Easy Discharge – Conical shape with central outlet for high yield.

Materials of Construction (MOC):

• SS304, SS316, MSIS2062

• Optional internal coatings: PFA, PTFE, Halar (for corrosion/chemical resistance).

Design Standards:

• ASME, API, CGMP (meets pharma/chemical requirements).

Capacity Range:

• 5L to 500L (scalable for lab/pilot/production).

Industries Served:

1. Pharmaceutical (granulation, coating, drying).

2. Chemical (pigments, agglomeration, dispersion).

Advantages Over Conventional Mixers:

✅ Faster mixing (short batch times).
✅ Multi-functional (replaces multiple equipment).
✅ CGMP compliance for regulated industries.
✅ Easy cleaning & maintenance (no product contact with seals).